VBP1
The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. Because it functions as a chaperone protein, it is suspected that it may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. [provided by RefSeq]
Full Name
von Hippel-Lindau binding protein 1
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Biological Process
Biological Process microtubule-based process Source:GO_Central1 Publication
Biological Process negative regulation of amyloid fibril formation Source:FlyBase1 Publication
Biological Process protein folding Source:FlyBase1 Publication
Biological Process protein stabilization Source:ComplexPortal1 Publication
Biological Process tubulin complex assembly Source:GO_Central1 Publication
Biological Process negative regulation of amyloid fibril formation Source:FlyBase1 Publication
Biological Process protein folding Source:FlyBase1 Publication
Biological Process protein stabilization Source:ComplexPortal1 Publication
Biological Process tubulin complex assembly Source:GO_Central1 Publication
Cellular Location
Cytoplasm
Nucleus
In complex with VHL can translocate to the nucleus.
Nucleus
In complex with VHL can translocate to the nucleus.
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Anti-VBP1 antibodies
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Target: VBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D11
Application*: E, WB
Target: VBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Dog, Monkey
Clone: 2G2
Application*: WB, P
Target: VBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1H5
Application*: E, LA
Target: VBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1320
Application*: IH
Target: VBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Rat, Monkey, Mouse
Clone: CBYY-1319
Application*: WB, IH
Target: VBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1318
Application*: WB, IH
Target: VBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-1317
Application*: WB, IH
Target: VBP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Dog, Rat, Monkey, Mouse
Clone: CBYY-1316
Application*: WB, IH
Target: VBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Rat, Monkey, Mouse
Clone: CBYY-1315
Application*: WB, IH
Target: VBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1314
Application*: WB, IH
Target: VBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Dog, Rat, Monkey, Mouse
Clone: CBYY-1313
Application*: WB, IH
Target: VBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-1312
Application*: E, IH, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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