Mouse Anti-VBP1 Recombinant Antibody (CBYY-1318) (CBMAB-1352-YY)

Name: Mouse Anti-VBP1 Recombinant Antibody (CBYY-1318)
SKU: CBMAB-1352-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYY-1318

Application

WB, IHC

Immunogen

Full length human recombinant protein of human VBP1(NP_003363) produced in HEK293T cell

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

von Hippel-Lindau binding protein 1

Introduction

The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforMouse.

Entrez Gene ID

7411

UniProt ID

P61758

Alternative Names

VHL Binding Protein 1; Von Hippel-Lindau Binding Protein 1; HIBBJ46; PFDN3; VBP-1; Von Hippel-Lindau-Binding Protein 1;

Function

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Biological Process

Biological Process microtubule-based process Source:GO_Central1 Publication
Biological Process negative regulation of amyloid fibril formation Source:FlyBase1 Publication
Biological Process protein folding Source:FlyBase1 Publication
Biological Process protein stabilization Source:ComplexPortal1 Publication
Biological Process tubulin complex assembly Source:GO_Central1 Publication

Cellular Location

Cytoplasm
Nucleus
In complex with VHL can translocate to the nucleus.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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