WFDC2
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]
Full Name
WAP Four-Disulfide Core Domain 2
Function
Broad range protease inhibitor.
Biological Process
Biological Process antibacterial humoral response Source:GO_Central1 Publication
Biological Process innate immune response Source:GO_Central1 Publication
Biological Process proteolysis Source:ProtInc1 Publication
Biological Process spermatogenesis Source:ProtInc1 Publication
Biological Process innate immune response Source:GO_Central1 Publication
Biological Process proteolysis Source:ProtInc1 Publication
Biological Process spermatogenesis Source:ProtInc1 Publication
Cellular Location
Secreted
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Anti-WFDC2 antibodies
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CompareTarget: WFDC2
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBWJW-029
Application*: E, WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A9
Application*: WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB310A
Application*: ELISA
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A1B2
Application*: E
Target: WFDC2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-174
Tag: His Tag
Target: WFDC2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-124
Tag: His Tag
Target: WFDC2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-124
Tag: hFc Tag
Target: WFDC2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 17D2
Application*: E, WB, F
Target: WFDC2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: CBFYH-3680
Application*: P
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-3679
Application*: E, WB
Target: WFDC2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Human
Clone: CBFYH-2839
Application*: WB, IP, IC, F
Target: WFDC2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-2837
Application*: P
Target: WFDC2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-2836
Application*: E, WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2834
Application*: WB, IH
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2852
Application*: IH
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4C9C6C11
Application*: E
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4C5D8
Application*: E, WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-3317
Application*: E, WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYE-1687
Application*: E
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-225
Application*: P
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-226
Application*: P
Target: WFDC2
Host: Rabbit
Specificity: Human
Clone: CBWJW-222
Application*: F, IC, P, WB
Target: WFDC2
Host: Mouse
Specificity: Human
Clone: CBWJW-110
Application*: E
Target: WFDC2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJW-093
Application*: E
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-091
Application*: E, WB
Target: WFDC2
Host: Mouse
Specificity: Human
Clone: CBWJW-031
Application*: WB, IC, P, C, E
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-030
Application*: P, WB, E
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJW-028
Application*: E, WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-027
Application*: E, WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-026
Application*: E, WB, P
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-025
Application*: E
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-197
Application*: P
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5C2A5
Application*: E
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3F9
Application*: E, WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A7
Application*: P, WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G7
Application*: WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-206
Application*: P, WB
Target: WFDC2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A23
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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