ZNF397
This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined. [provided by RefSeq, Oct 2009]
Full Name
Zinc Finger Protein 397
Function
Isoform 3 acts as a DNA-dependent transcriptional repressor.
Biological Process
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Isoform 1
Nucleus
Isoform 3
Nucleus
Cytoplasm
Nucleus
Isoform 3
Nucleus
Cytoplasm
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Anti-ZNF397 antibodies
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Target: ZNF397
Specificity: Human
Target: ZNF397
Specificity: Human
Target: ZNF397
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F3
Application*: IF, WB
Target: ZNF397
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1F8
Application*: E, P, WB
Target: ZNF397
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6B9
Application*: IP, M
Target: ZNF397
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2F6
Application*: IP, M, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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