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Mouse Anti-ZNF397 Recombinant Antibody (1F8) (CBMAB-Z0559-WJ)

This product is a mouse antibody that recognizes ZNF397. The antibody 1F8 can be used for immunoassay techniques such as: ELISA, IHC-P, WB.
See all ZNF397 antibodies
Published Data
Fig.1 Immunofluorescence analysis of GFP:mouse Zfp397 or human ZNF397 constructs in human and mouse cells.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
1F8
Antibody Isotype
IgG2a, κ
Application
ELISA, IHC-P, WB

Basic Information

Immunogen
ZNF396 (AA131-230) partial recombinant protein with GST tag. Immunogen sequence: ERELDGPKQI FFGRRKDMIA EKLAPSEITE ELPSSQLMPV KKQLQGASWE LQSLRPHDED IKTTNVKSAS RQKTSLGIEL HCNVSNILHM NGSQSSTYRG
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.5 mg/mL

Target

Full Name
Zinc Finger Protein 397
Introduction
This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined. Isoform 3 acts as a DNA-dependent transcriptional repressor.
Entrez Gene ID
84307
UniProt ID
Q8NF99
Alternative Names
MGC13250; ZNF47; ZSCAN15
Function
Isoform 3 acts as a DNA-dependent transcriptional repressor.
Biological Process
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Isoform 1
Nucleus
Isoform 3
Nucleus
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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