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Rabbit Anti-BST1 Recombinant Antibody (29) (CBMAB-C4544-LY)

This product is antibody recognizes BST1. The antibody 29 immunoassay techniques such as: ELISA, WB.
See all BST1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
29
Antibody Isotype
IgG
Application
ELISA, WB

Basic Information

Immunogen
Recombinant Human CD157/BST1 Protein. This antibody was obtained from a rabbit immunized with purified, recombinant Human CD157/BST1
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Bone Marrow Stromal Cell Antigen 1
Introduction
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Entrez Gene ID
683
UniProt ID
Q10588
Alternative Names
Bone Marrow Stromal Cell Antigen 1; ADP-Ribosyl Cyclase 2; Bone Marrow Stromal Antigen 1; Cyclic ADP-Ribose Hydrolase 2; NAD(+) Nucleosidase; CADPr Hydrolase 2;
Function
Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Biological Process
Humoral immune response Source: ParkinsonsUK-UCL
NAD metabolic process Source: Reactome
Neutrophil degranulation Source: Reactome
Positive regulation of B cell proliferation Source: GO_Central
Positive regulation of cell population proliferation Source: ParkinsonsUK-UCL
Regulation of actin cytoskeleton organization Source: ParkinsonsUK-UCL
Regulation of calcium-mediated signaling Source: ParkinsonsUK-UCL
Regulation of cell-matrix adhesion Source: ParkinsonsUK-UCL
Regulation of cellular extravasation Source: ParkinsonsUK-UCL
Regulation of inflammatory response Source: ParkinsonsUK-UCL
Regulation of integrin-mediated signaling pathway Source: ParkinsonsUK-UCL
Regulation of neutrophil chemotaxis Source: ParkinsonsUK-UCL
Regulation of peptidyl-tyrosine phosphorylation Source: ParkinsonsUK-UCL
Regulation of superoxide metabolic process Source: ParkinsonsUK-UCL
Signal transduction Source: ParkinsonsUK-UCL
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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