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BST1

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Full Name
Bone Marrow Stromal Cell Antigen 1
Function
Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Biological Process
Humoral immune response Source: ParkinsonsUK-UCL
NAD metabolic process Source: Reactome
Neutrophil degranulation Source: Reactome
Positive regulation of B cell proliferation Source: GO_Central
Positive regulation of cell population proliferation Source: ParkinsonsUK-UCL
Regulation of actin cytoskeleton organization Source: ParkinsonsUK-UCL
Regulation of calcium-mediated signaling Source: ParkinsonsUK-UCL
Regulation of cell-matrix adhesion Source: ParkinsonsUK-UCL
Regulation of cellular extravasation Source: ParkinsonsUK-UCL
Regulation of inflammatory response Source: ParkinsonsUK-UCL
Regulation of integrin-mediated signaling pathway Source: ParkinsonsUK-UCL
Regulation of neutrophil chemotaxis Source: ParkinsonsUK-UCL
Regulation of peptidyl-tyrosine phosphorylation Source: ParkinsonsUK-UCL
Regulation of superoxide metabolic process Source: ParkinsonsUK-UCL
Signal transduction Source: ParkinsonsUK-UCL
Cellular Location
Cell membrane
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Anti-BST1 antibodies

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Mouse Anti-BST1 Recombinant Antibody (4C2) (CBMAB-A0891-LY)

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Target: BST1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4C2
Application*: WB, E
Datasheet SDS

Rat Anti-BST1 Recombinant Antibody (KT157) (CBMAB-C9507-LY)

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Target: BST1
Host: Rat
Antibody Isotype: IgG2c
Specificity: Mouse
Clone: KT157
Application*: FC
Datasheet SDS

Rabbit Anti-BST1 Recombinant Antibody (CBFYC-0584) (CBMAB-C0638-FY)

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Target: BST1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-0584
Application*: E
Datasheet SDS

Mouse Anti-BST1 Recombinant Antibody (CBYY-2090) (CBMAB-2439-YY)

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Target: BST1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-2090
Application*: FC
Datasheet SDS

Mouse Anti-BST1 Recombinant Antibody (CBT2549) (V2LY-0625-LY1888)

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Target: BST1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Rat
Clone: CBT2549
Application*: WB, F
Datasheet SDS

Mouse Anti-BST1 Recombinant Antibody (CBT2950) (V2LY-0625-LY1887)

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Target: BST1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBT2950
Application*: WB, IH, F
Datasheet SDS

BST1 Matched Antibody Pair (144) (APMAB-144LY)

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Target: BST1
Specificity: Human
Datasheet SDS

Mouse Anti-BST1 Recombinant Antibody (C5315) (CBMAB-C5315-CQ)

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Target: BST1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C5315
Application*: E
Datasheet SDS

Mouse Anti-BST1 Recombinant Antibody (CBXC-0856) (CBMAB-C1971-CQ)

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Target: BST1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0856
Application*: FC
Datasheet SDS

Mouse Anti-BST1 Recombinant Antibody (CBYY-C0782) (CBMAB-C2218-YY)

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Target: BST1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0782
Application*: WB, IP, IF, P, FC
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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