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Mouse Anti-14-3-3 Pan Recombinant Antibody (V2-9272) (CBMAB-1181-LY)

This product is antibody recognizes 14-3-3 Pan. The antibody 3F7 immunoassay techniques such as: IP, WB.
See all 14-3-3 Pan antibodies
Published Data
Mouse Anti-14-3-3 Pan Recombinant Antibody (3F7) (CBMAB-1181-LY) in WB
Western-blot analysis of selected target proteins confirmed TXNL1, CAPZA1, and HDAC2 as significantly differentially expressed proteins (highlighted in bold). TXNL1 and CAPZA1 are significantly lower expressed in aneuploid cell lines whereas HDAC2 significantly higher expressed in aneuploid cell lines (*Fold change calculation for western blot (WB) and two-dimensional gel electrophoresis (2-DE): aneuploid over diploid) ...View More
Gemoll, T., Roblick, U. J., Szymczak, S., Braunschweig, T., Becker, S., Igl, B. W., ... & Habermann, J. K. (2011). HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers. Cellular and Molecular Life Sciences, 68, 3261-3274.

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-9272
Antibody Isotype
IgG1
Application
IP, WB

Basic Information

Immunogen
Full length protein.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
14-3-3 Pan
Introduction
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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