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Mouse Anti-C1D Recombinant Antibody (CBFYC-0593) (CBMAB-C0647-FY)

This product is mouse antibody that recognizes C1D. The antibody CBFYC-0593 can be used for immunoassay techniques such as: ELISA.
See all C1D antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-0593
Antibody Isotype
IgG1
Application
ELISA

Basic Information

Immunogen
Recombinant Human C1D protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
nuclear DNA-binding protein
Introduction
The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus.
Entrez Gene ID
10438
UniProt ID
Q13901
Alternative Names
LRP1; hC1D; Rrp47; SUNCOR; SUN-CoR
Function
Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity).
Biological Process
Apoptotic process Source: UniProtKB-KW
Maturation of 5.8S rRNA Source: UniProtKB
Regulation of gene expression Source: GO_Central
rRNA processing Source: Reactome
Cellular Location
Nucleus; Nucleolus; Cytoplasm. EXOSC10 is required for nucleolar localization (PubMed:17412707). Colocalizes with TSNAX in the nucleus (PubMed:11801738).
PTM
Phosphorylated by PRKDC.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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