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Mouse Anti-CALB1 Recombinant Antibody (CBXC-2609) (CBMAB-C0270-CQ)

This product is a mouse antibody that recognizes CALB1. The antibody CBXC-2609 can be used for immunoassay techniques such as: WB, IF.
See all CALB1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat, Pig, Cattle, Chicken, Horse
Clone
CBXC-2609
Antibody Isotype
IgG2a
Application
WB, IF

Basic Information

Immunogen
Full length recombinant human Calbindin D-28K. [UniProt# P05937]
Specificity
Human, Mouse, Rat, Pig, Cattle, Chicken, Horse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Calbindin 1
Introduction
CALB1 (Calbindin 1) is a Protein Coding gene. Diseases associated with CALB1 include Huntington Disease and Temporal Lobe Epilepsy. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Endocrine and other factor-regulated calcium reabsorption. Gene Ontology (GO) annotations related to this gene include calcium ion binding and vitamin D binding. An important paralog of this gene is CALB2.
Entrez Gene ID
Human793
Mouse12307
Rat83839
Chicken396519
Horse100034057
Cattle539930
Pig100153645
UniProt ID
HumanP05937
MouseP12658
RatP07171
ChickenP04354
HorseF7D4N3
CattleP04467
PigB3VFB6
Alternative Names
Calbindin 1; Vitamin D-Dependent Calcium-Binding Protein, Avian-Type; Calbindin 1, 28kDa; Calbindin D28; D-28K; Calbindin 1, (28kD);
Function
Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
Biological Process
Amyloid fibril formation Source: Reactome
Cellular response to organic substance Source: Ensembl
Cochlea development Source: Ensembl
Locomotory behavior Source: Ensembl
Long-term memory Source: UniProtKB
Metanephric collecting duct development Source: Ensembl
Metanephric connecting tubule development Source: Ensembl
Metanephric distal convoluted tubule development Source: Ensembl
Metanephric part of ureteric bud development Source: Ensembl
Regulation of cytosolic calcium ion concentration Source: GO_Central
Regulation of long-term synaptic potentiation Source: GO_Central
Regulation of presynaptic cytosolic calcium ion concentration Source: GO_Central
Retina layer formation Source: Ensembl
Short-term memory Source: UniProtKB
Cellular Location
Cuticular plate; Cytosol; Postsynaptic cytosol; Presynaptic cytosol; Extracellular exosome; Nucleus; Axon; Calyx of Held; Dendrite; Dendritic spine; GABA-ergic synapse; Glutamatergic synapse; Hippocampal mossy fiber to CA3 synapse; Neuron projection; Neuronal cell body; Stereocilium; Synapse; Terminal bouton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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