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Mouse Anti-CARTPT (AA 37-116) Recombinant Antibody (CBFYC-0819) (CBMAB-C0874-FY)

This product is mouse antibody that recognizes CARTPT. The antibody CBFYC-0819 can be used for immunoassay techniques such as: WB, IHC.
See all CARTPT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-0819
Antibody Isotype
IgG2b
Application
WB, IHC

Basic Information

Immunogen
E. coli-derived recombinant human CART, Ala37-Leu116
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 37-116

Target

Full Name
CART Prepropeptide
Introduction
This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans.
Entrez Gene ID
9607
UniProt ID
Q16568
Alternative Names
CART Prepropeptide; CART; Cocaine-And Amphetamine-Regulated Transcript Protein; Cocaine And Amphetamine Regulated Transcript
Function
Satiety factor closely associated with the actions of leptin and neuropeptide Y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro.
Biological Process
Activation of MAPKK activity Source: HGNC-UCL
Adult feeding behavior Source: HGNC-UCL
Cell-cell signaling Source: ProtInc
Cellular glucose homeostasis Source: HGNC-UCL
Cellular response to starvation Source: HGNC-UCL
Chemical synaptic transmission Source: UniProtKB-KW
Circadian regulation of gene expression Source: HGNC-UCL
G protein-coupled receptor signaling pathway Source: HGNC-UCL
Negative regulation of appetite Source: HGNC-UCL
Negative regulation of bone resorption Source: HGNC-UCL
Negative regulation of glucagon secretion Source: Ensembl
Negative regulation of osteoclast differentiation Source: HGNC-UCL
Neuropeptide signaling pathway Source: UniProtKB-KW
Positive regulation of blood pressure Source: HGNC-UCL
Positive regulation of epinephrine secretion Source: HGNC-UCL
Positive regulation of transmission of nerve impulse Source: HGNC-UCL
Regulation of insulin secretion Source: Ensembl
Signal transduction Source: ProtInc
Somatostatin secretion Source: Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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