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Rat Anti-CCL28 Recombinant Antibody (CBFYC-0981) (CBMAB-C1037-FY)

This product is rat antibody that recognizes CCL28. The antibody CBFYC-0981 can be used for immunoassay techniques such as: WB, Neut.
See all CCL28 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBFYC-0981
Antibody Isotype
IgG2b
Application
WB, Neut

Basic Information

Immunogen
E. coli-derived recombinant mouse CCL28, Ile23-Arg130
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
chemokine (C-C motif) ligand 28
Introduction
Tumour hypoxia promotes the recruitment of regulatory T (Treg) cells through induction of expression of the chemokine CC-chemokine ligand 28 (CCL28), which, in turn, promotes tumour tolerance and angiogenesis.
Entrez Gene ID
56838
UniProt ID
Q9JIL2
Alternative Names
Ccl28 chemokine (C-C motif) ligand 28
Function
Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell chemotaxis Source: UniProtKB
Chemotaxis Source: UniProtKB
Cytolysis in other organism Source: UniProtKB
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: InterPro
Killing of cells of other organism Source: UniProtKB
Negative regulation of leukocyte tethering or rolling Source: UniProtKB
Positive regulation of cell-matrix adhesion Source: UniProtKB
Positive regulation of cytosolic calcium ion concentration Source: Ensembl
Response to nutrient Source: Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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