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CCL28

This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. [provided by RefSeq]
Full Name
chemokine (C-C motif) ligand 28
Function
Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell chemotaxis Source: UniProtKB
Chemotaxis Source: UniProtKB
Cytolysis in other organism Source: UniProtKB
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: InterPro
Killing of cells of other organism Source: UniProtKB
Negative regulation of leukocyte tethering or rolling Source: UniProtKB
Positive regulation of cell-matrix adhesion Source: UniProtKB
Positive regulation of cytosolic calcium ion concentration Source: Ensembl
Response to nutrient Source: Ensembl
Cellular Location
Secreted

Anti-CCL28 antibodies

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Target: CCL28
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 134315
Application*: EC
Target: CCL28
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 134306
Application*: WB, N
Target: CCL28
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-3131
Application*: WB, N
Target: CCL28
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1266
Application*: WB, EC
Target: CCL28
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0982
Application*: E
Target: CCL28
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYC-0981
Application*: WB, N
Target: CCL28
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-0980
Application*: EC
Target: CCL28
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: RM0179-7N12
Application*: WB, B/N
Target: CCL28
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0153-9G34
Application*: WB, N
Target: CCL28
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-C1087
Application*: N, WB
Target: CCL28
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1085
Application*: WB, N
Target: CCL28
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9G34
Application*: WB, N
Target: CCL28
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 15
Application*: E
Target: CCL28
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 012
Application*: E
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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