Rat Anti-CCL28 Recombinant Antibody (134315) (CBMAB-C2719-LY)

Name: Rat Anti-CCL28 Recombinant Antibody (134315)
SKU: CBMAB-C2719-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

134315

Application

ELISA

Immunogen

E. coli-derived recombinant mouse CCL28, Ile23-Arg130.

Host Species

Rat

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, Trehalose

Preservative

None

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

chemokine (C-C motif) ligand 28

Entrez Gene ID

56838

UniProt ID

Q9JIL2

Function

Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.

Biological Process

Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell chemotaxis Source: UniProtKB
Chemotaxis Source: UniProtKB
Cytolysis in other organism Source: UniProtKB
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: InterPro
Killing of cells of other organism Source: UniProtKB
Negative regulation of leukocyte tethering or rolling Source: UniProtKB
Positive regulation of cell-matrix adhesion Source: UniProtKB
Positive regulation of cytosolic calcium ion concentration Source: Ensembl
Response to nutrient Source: Ensembl

Cellular Location

Secreted

Iwamoto, R., Takahashi, T., Yoshimi, K., Imai, Y., Koide, T., Hara, M., ... & Yukita, A. (2021). Chemokine ligand 28 (CCL28) negatively regulates trabecular bone mass by suppressing osteoblast and osteoclast activities. Journal of Bone and Mineral Metabolism, 1-14.

Liu, B., & Wei, C. (2021). Hypoxia Induces Overexpression of CCL28 to Recruit Treg Cells to Enhance Angiogenesis in Lung Adenocarcinoma. Journal of Environmental Pathology, Toxicology and Oncology, 40(1).

Noor, S., Qousain, S. T., & Muhammad, S. A. (2019). In silico docking analysis of CCL28 (CC motif chemokine ligand 28) and astragalin as the potential inhibitor of rheumatoid arthritis. F1000Research, 8(313), 313.

Wang, P., Qi, X., Xu, G., Liu, J., Guo, J., Li, X., ... & Sun, H. (2019). CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells. Aging (Albany NY), 11(18), 7402.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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