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Mouse Anti-CCNL1 (AA 1-173) Recombinant Antibody (CBFYC-1059) (CBMAB-C1116-FY)

This product is mouse antibody that recognizes CCNL1. The antibody CBFYC-1059 can be used for immunoassay techniques such as: IF, WB.
See all CCNL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-1059
Antibody Isotype
IgG1, k
Application
IF, WB

Basic Information

Immunogen
Full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, k
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-173

Target

Full Name
cyclin L1
Introduction
CCNL1 (Cyclin L1) is a Protein Coding gene. Diseases associated with CCNL1 include Squamous Cell Carcinoma, Head And Neck. Gene Ontology (GO) annotations related to this gene include protein kinase binding. An important paralog of this gene is CCNL2.
Entrez Gene ID
57018
UniProt ID
Q9UK58
Alternative Names
Cyclin L1; Cyclin-L; Cyclin L Ania-6a; Cyclin L Gamma; Cyclin-L1; PRO1073; Ania-6a; ANIA6A; BM-001
Function
Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) (PubMed:18216018).
Inhibited by the CDK-specific inhibitor CDKN1A/p21 (PubMed:11980906).
May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) (PubMed:12414649, PubMed:15700036).
Biological Process
Regulation of transcription by RNA polymerase II Source: GO_Central
RNA processing Source: InterPro
Cellular Location
Nucleus speckle; Nucleoplasm. Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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