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Mouse Anti-CCNL1 Recombinant Antibody (CBYY-C1127) (CBMAB-C2564-YY)

This product is mouse antibody that recognizes CCNL1. The antibody CBYY-C1127 can be used for immunoassay techniques such as: ELISA, WB, ICC, IHC
See all CCNL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C1127
Antibody Isotype
IgG2a, κ
Application
ELISA, WB, ICC, IHC

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
cyclin L1
Entrez Gene ID
57018
UniProt ID
Q9UK58
Alternative Names
NEP; SFE; CD10; CALLA; CMT2T; SCA43
Function
Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) (PubMed:18216018).
Inhibited by the CDK-specific inhibitor CDKN1A/p21 (PubMed:11980906).
May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) (PubMed:12414649, PubMed:15700036).
Biological Process
Regulation of transcription by RNA polymerase II Source: GO_Central
RNA processing Source: InterPro
Cellular Location
Nucleus speckle; Nucleoplasm. Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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