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Rabbit Anti-CDK5R2 Recombinant Antibody (EPR5075(2)) (CBMAB-1343-CN)

This product is a rabbit antibody that recognizes CDK5R2 of human. The antibody EPR5075(2) can be used for immunoassay techniques such as: IF, IP, WB.
See all CDK5R2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EPR5075(2)
Antibody Isotype
IgG
Application
IF, IP, WB

Basic Information

Immunogen
A synthetic peptide corresponding to residues in Human p39.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
49% PBS, 50% Glycerol, 0.05% BSA, pH 7.2
Preservative
0.01% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cyclin Dependent Kinase 5 Regulatory Subunit 2
Introduction
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. Activator of CDK5/TPKII.
Entrez Gene ID
Human8941
Mouse12570
Rat501164
UniProt ID
HumanQ13319
MouseO35926
RatF1M491
Alternative Names
P39; NCK5AI; p39nck5ai
Function
Activator of CDK5/TPKII.
Biological Process
Cerebellum development Source: Ensembl
Hippocampus development Source: Ensembl
Layer formation in cerebral cortex Source: Ensembl
Neuron migration Source: Ensembl
Positive regulation of calcium ion-dependent exocytosis Source: Ensembl
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: ProtInc
Superior olivary nucleus maturation Source: Ensembl
Cellular Location
Cell membrane
PTM
Myristoylated. The Gly-2-Ala mutant is absent of the cell periphery, suggesting that a proper myristoylation signal is essential for the proper distribution of CDK5R2 (p39).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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