CDK5R2

CDK5R2 (Cyclin Dependent Kinase 5 Regulatory Subunit 2) is a Protein Coding gene. Among its related pathways are Lissencephaly gene (LIS1) in neuronal migration and development and Reelin Pathway (Cajal-Retzius cells). Gene Ontology (GO) annotations related to this gene include lipid binding and cyclin-dependent protein kinase 5 activator activity. An important paralog of this gene is CDK5R1.

Full Name

Cyclin Dependent Kinase 5 Regulatory Subunit 2

Function

Activator of CDK5/TPKII.

Biological Process

Cerebellum development Source: Ensembl
Hippocampus development Source: Ensembl
Layer formation in cerebral cortex Source: Ensembl
Neuron migration Source: Ensembl
Positive regulation of calcium ion-dependent exocytosis Source: Ensembl
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: ProtInc
Superior olivary nucleus maturation Source: Ensembl

Cellular Location

Cell membrane

PTM

Myristoylated. The Gly-2-Ala mutant is absent of the cell periphery, suggesting that a proper myristoylation signal is essential for the proper distribution of CDK5R2 (p39).

Anti-CDK5R2 antibodies

Rabbit Anti-CDK5R2 Recombinant Antibody (EG608) (CBMAB-EN733-LY)

Datasheet

SDS

Target: CDK5R2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: EG608

Application*: WB: 1:500~1:1000 ELISA: 1:20000

Rabbit Anti-CDK5R2 Recombinant Antibody (CBYC-P045) (CBMAB-P0176-YC)

Datasheet

SDS

Target: CDK5R2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBYC-P045

Application*: WB, IP, IC, IF

Rabbit Anti-CDK5R2 Recombinant Antibody (CBYC-P044) (CBMAB-P0175-YC)

Datasheet

SDS

Target: CDK5R2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBYC-P044

Application*: P, IP, WB

Rabbit Anti-CDK5R2 Recombinant Antibody (EPR5075(2)) (CBMAB-1343-CN)

Datasheet

SDS

Target: CDK5R2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EPR5075(2)

Application*: IF, IP, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)