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Mouse Anti-CDKL3 Recombinant Antibody (CBYY-C1798) (CBMAB-C3236-YY)

This product is mouse antibody that recognizes CDKL3. The antibody CBYY-C1798 can be used for immunoassay techniques such as: ELISA, WB
See all CDKL3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C1798
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa322-420 from human CDKL3 (AAH41799) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein A purified
Preservative
PBS, pH 7.2
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cyclin Dependent Kinase Like 3
Entrez Gene ID
51265
UniProt ID
Q8IVW4
Alternative Names
Corneodesmosin; Differentiated Keratinocyte S Protein; S Protein; HTSS1; HYPT2; PSS1; HTSS; PSS; S;
Biological Process
Cellular protein modification process Source: ProtInc
Dendrite extension Source: GO_Central
Negative regulation of axon extension Source: GO_Central
Positive regulation of dendrite morphogenesis Source: GO_Central
Protein phosphorylation Source: GO_Central
Cellular Location
Cytoplasm

Zeng, D. X., Sheng, G. F., Liu, Y. P., Zhang, Y. P., Qian, Z., Li, Z., & Bi, Y. Z. (2021). Cyclin-dependent kinase like 3 promotes triple-negative breast cancer progression via inhibiting the p53 signaling pathway. Neoplasma.

Yan, S., Wei, H., Li, Q., Si, M., Feng, W., & Chen, Z. (2021). CircTP53 promotes colorectal cancer by acting as a miR-876-3p sponge to increase cyclin-dependent kinase-like 3 expression. Cellular Signalling, 78, 109845.

Cui, Y., Yang, Z., Wang, H., Yan, Y., Huang, Q., Gong, Z., ... & Xu, T. (2021). Identification of CDKL3 as a critical regulator in development of glioma through regulating RRM2 and the JNK signaling pathway. Cancer science, 112(8), 3150.

Sun, Q., Zhang, X., Tan, Z., Gu, H., Ding, S., & Ji, Y. (2021). Bone marrow mesenchymal stem cells-secreted exosomal microRNA-205–5p exerts inhibitory effect on the progression of liver cancer through regulating CDKL3. Pathology-Research and Practice, 225, 153549.

He, A., Ma, L., Huang, Y., Zhang, H., Duan, W., Li, Z., ... & Xiang, D. (2020). CDKL3 promotes osteosarcoma progression by activating Akt/PKB. Life science alliance, 3(5).

Zhou, S., Zhang, M., Zhou, C., Wang, W., Yang, H., & Ye, W. (2020). CDKL3 Targets ATG5 to Promote Carcinogenesis of Esophageal Squamous Cell Carcinoma. Frontiers in Oncology, 10, 1602.

Zhang, J., Su, G., Tang, Z., Wang, L., Fu, W., Zhao, S., ... & Xie, X. (2018). Curcumol exerts anticancer effect in cholangiocarcinoma cells via down-regulating CDKL3. Frontiers in physiology, 9, 234.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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