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Mouse Anti-CEACAM4 Recombinant Antibody (11D36) (CBMAB-C2499-LY)

This product is antibody recognizes CEACAM4. The antibody 11D36 immunoassay techniques such as: ELISA, WB.
See all CEACAM4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
11D36
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Immunogen
Recombinant corresponding to human CEACAM-4 expressed in E. coli (O75871)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
5% trehalose
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 4
Introduction
CEACAM4 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 4) is a Protein Coding gene. Diseases associated with CEACAM4 include Colorectal Cancer.


An important paralog of this gene is CEACAM6.
Entrez Gene ID
1089
UniProt ID
O75871
Alternative Names
Carcinoembryonic Antigen Related Cell Adhesion Molecule 4; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 4; Non-Specific Cross-Reacting Antigen W236; Carcinoembryonic Antigen CGM7; CGM7; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 4-Sv1; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 4-Sv2;
Function
Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.
Biological Process
Phagocytosis Source: UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 36-155
Helical: 156-176
Cytoplasmic: 177-244
PTM
N-glycosylated.
The cytoplasmic ITAM-like sequence becomes tyrosine phosphorylated by SRC family PTKs upon ligand-mediated receptor clustering and allows to initiate phagocytosis of bound ligand.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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