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CEACAM4

CEACAM4 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 4) is a Protein Coding gene.
Diseases associated with CEACAM4 include Colorectal Cancer.

An important paralog of this gene is CEACAM6.

Full Name

Carcinoembryonic Antigen Related Cell Adhesion Molecule 4

Function

Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.

Biological Process

Phagocytosis Source: UniProtKB

Cellular Location

Membrane

Topology

Extracellular: 36-155
Helical: 156-176
Cytoplasmic: 177-244

PTM

N-glycosylated.
The cytoplasmic ITAM-like sequence becomes tyrosine phosphorylated by SRC family PTKs upon ligand-mediated receptor clustering and allows to initiate phagocytosis of bound ligand.

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Anti-CEACAM4 antibodies

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Mouse Anti-CEACAM4 Recombinant Antibody (CBXC-1330) (CBMAB-C1598-CQ)

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Target: CEACAM4

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXC-1330

Application*: F

Mouse Anti-CEACAM4 Recombinant Antibody (CBYY-C0332) (CBMAB-C1106-YY)

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Target: CEACAM4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C0332

Application*: WB, IH

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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