CEACAM4

CEACAM4 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 4) is a Protein Coding gene.
Diseases associated with CEACAM4 include Colorectal Cancer.

An important paralog of this gene is CEACAM6.

Full Name

Carcinoembryonic Antigen Related Cell Adhesion Molecule 4

Function

Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.

Biological Process

Phagocytosis Source: UniProtKB

Cellular Location

Membrane

Topology

Extracellular: 36-155
Helical: 156-176
Cytoplasmic: 177-244

PTM

N-glycosylated.
The cytoplasmic ITAM-like sequence becomes tyrosine phosphorylated by SRC family PTKs upon ligand-mediated receptor clustering and allows to initiate phagocytosis of bound ligand.

Anti-CEACAM4 antibodies

Mouse Anti-CEACAM4 Recombinant Antibody (CBXC-1330) (CBMAB-C1598-CQ)

Datasheet

SDS

Target: CEACAM4

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXC-1330

Application*: F

Mouse Anti-CEACAM4 Recombinant Antibody (CBFYC-1677) (CBMAB-C1739-FY)

Datasheet

SDS

Target: CEACAM4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-1677

Application*: E, WB

Mouse Anti-CEACAM4 Recombinant Antibody (MM0692-7J24) (CBMAB-C10868-LY)

Datasheet

SDS

Target: CEACAM4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: MM0692-7J24

Application*: WB, P

Mouse Anti-CEACAM4 Recombinant Antibody (CBYY-C0332) (CBMAB-C1106-YY)

Datasheet

SDS

Target: CEACAM4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C0332

Application*: WB, IH

Mouse Anti-CEACAM4 Recombinant Antibody (11D36) (CBMAB-C2499-LY)

Datasheet

SDS

Target: CEACAM4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 11D36

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)