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CEACAM4

CEACAM4 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 4) is a Protein Coding gene.
Diseases associated with CEACAM4 include Colorectal Cancer.


An important paralog of this gene is CEACAM6.
Full Name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 4
Function
Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.
Biological Process
Phagocytosis Source: UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 36-155
Helical: 156-176
Cytoplasmic: 177-244
PTM
N-glycosylated.
The cytoplasmic ITAM-like sequence becomes tyrosine phosphorylated by SRC family PTKs upon ligand-mediated receptor clustering and allows to initiate phagocytosis of bound ligand.
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Anti-CEACAM4 antibodies

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Mouse Anti-CEACAM4 Recombinant Antibody (CBXC-1330) (CBMAB-C1598-CQ)

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Target: CEACAM4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1330
Application*: F
Datasheet SDS

Mouse Anti-CEACAM4 Recombinant Antibody (CBYY-C0332) (CBMAB-C1106-YY)

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Target: CEACAM4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0332
Application*: WB, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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