Mouse Anti-CEACAM4 Recombinant Antibody (CBXC-1330) (CBMAB-C1598-CQ)

Name: Mouse Anti-CEACAM4 Recombinant Antibody (CBXC-1330)
SKU: CBMAB-C1598-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBXC-1330

Application

Immunogen

Recombinant human CEACAM-4, Phe36-Val140.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
FC	2.5 µg/10^6 cells

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, 5% trehalose

Preservative

None

Concentration

0.2 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Carcinoembryonic Antigen Related Cell Adhesion Molecule 4

Introduction

CEACAM4 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 4) is a Protein Coding gene. Diseases associated with CEACAM4 include Colorectal Cancer. An important paralog of this gene is CEACAM6.

Entrez Gene ID

1089

UniProt ID

O75871

Alternative Names

Carcinoembryonic Antigen Related Cell Adhesion Molecule 4; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 4; Non-Specific Cross-Reacting Antigen W236; Carcinoembryonic Antigen CGM7; CGM7; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 4-Sv1; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 4-Sv2;

Function

Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.

Biological Process

Phagocytosis Source: UniProtKB

Cellular Location

Membrane

Topology

Extracellular: 36-155
Helical: 156-176
Cytoplasmic: 177-244

PTM

N-glycosylated.
The cytoplasmic ITAM-like sequence becomes tyrosine phosphorylated by SRC family PTKs upon ligand-mediated receptor clustering and allows to initiate phagocytosis of bound ligand.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-CEACAM4 Recombinant Antibody (CBYY-C0332) (CAT#: CBMAB-C1106-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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