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Mouse Anti-CLEC10A Recombinant Antibody (121A5.01) (CBMAB-C0248-LY)

This product is antibody recognizes CLEC10A. The antibody 121A5.01 immunoassay techniques such as: IHC, IP, IHC-F, FuncS.
See all CLEC10A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
121A5.01
Antibody Isotype
IgG1
Application
IHC, IP, IHC-F, FuncS

Basic Information

Immunogen
CD301 was used as immunogen
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
C-type lectin domain family 10, member A
Introduction
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Entrez Gene ID
10462
UniProt ID
Q8IUN9
Alternative Names
C-Type Lectin Domain Containing 10A; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 14 (Macrophage-Derived); Macrophage Lectin 2 (Calcium Dependent); C-Type Lectin Domain Family 10 Member A; CLECSF13; CLECSF14; HML;
Function
Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
Biological Process
Adaptive immune response Source: UniProtKB-KW
Endocytosis Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Stimulatory C-type lectin receptor signaling pathway Source: Reactome
Cellular Location
Membrane
Topology
Cytoplasmic: 1-39
Helical: 40-60
Extracellular: 61-316
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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