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CLEC10A

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Full Name
C-type lectin domain family 10, member A
Function
Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
Biological Process
Adaptive immune response Source: UniProtKB-KW
Endocytosis Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Stimulatory C-type lectin receptor signaling pathway Source: Reactome
Cellular Location
Membrane
Topology
Cytoplasmic: 1-39
Helical: 40-60
Extracellular: 61-316

Anti-CLEC10A antibodies

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Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBCNC-198
Application*: FC, C
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBCNC-197
Application*: E
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBCNC-196
Application*: FC, FN, C
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBCNC-013
Application*: FC, IF, IH
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBLC-LY-012
Application*: E, WB
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 8J187
Application*: F, IH
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 744812
Application*: F, MC
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2D6
Application*: E, WB
Target: CLEC10A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 019
Application*: E
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog
Clone: 125A10.03
Application*: IH, IP, C, FN
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 121A5.01
Application*: IH, IP, C, FN
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 10B1349
Application*: F, IH
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBWJC-2779
Application*: F, IH, IP
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: CBWJC-2778
Application*: F
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJC-2777
Application*: F
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: ER-MP23
Application*: F, IH
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2377
Application*: IH, IP, C, FN
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0461
Application*: E, WB
Target: CLEC10A
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0885
Application*: F
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog
Clone: CBXC-2383
Application*: F, IF
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-1911
Application*: F, IH
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-1910
Application*: F
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0239
Application*: F, IF
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E11
Application*: WB, E
Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 9G165
Application*: F
Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C1314
Application*: F
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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