CLEC10A

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Full Name
C-type lectin domain family 10, member A
Function
Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
Biological Process
Adaptive immune response Source: UniProtKB-KW
Endocytosis Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Stimulatory C-type lectin receptor signaling pathway Source: Reactome
Cellular Location
Membrane
Topology
Cytoplasmic: 1-39
Helical: 40-60
Extracellular: 61-316
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Anti-CLEC10A antibodies

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Mouse Anti-CLEC10A Recombinant Antibody (2D6) (CBMAB-C4910-LY)

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Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2D6
Application*: E, WB
Datasheet SDS

Mouse Recombinant CLEC10A protein, His Tag (V2LY-0526-LY8124)

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Target: CLEC10A
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 58-305
Tag: His Tag
Datasheet SDS

Mouse Recombinant CLEC10A protein, hFc Tag (V2LY-0526-LY8123)

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Target: CLEC10A
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 58-305
Tag: hFc Tag
Datasheet SDS

Human Recombinant CLEC10A protein, ECD, hFc Tag (V2LY-0526-LY3219)

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Target: CLEC10A
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 61-292
Tag: hFc Tag
Datasheet SDS

Mouse Anti-CLEC10A Recombinant Antibody (CBT2579) (V2LY-0625-LY1271)

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Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2579
Application*: F
Datasheet SDS

Mouse Anti-CLEC10A Recombinant Antibody (CBXC-0461) (V2LY-1206-LY77)

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Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0461
Application*: F, WB, IH, IP
Datasheet SDS

Mouse Anti-CLEC10A Recombinant Antibody (CBXC-2383) (V2LY-1206-LY76)

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Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-2383
Application*: F
Datasheet SDS

Rat Anti-CLEC10A Recombinant Antibody (CBFYC-1911) (V2LY-1206-LY74)

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Target: CLEC10A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-1911
Application*: WB, IP, IF, F
Datasheet SDS

Mouse Anti-CLEC10A Recombinant Antibody (CBFYC-1910) (V2LY-1206-LY73)

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Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1910
Application*: E, WB
Datasheet SDS

Mouse Anti-CLEC10A Recombinant Antibody (CBFYC-0239) (V2LY-1206-LY72)

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Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-0239
Application*: E, WB
Datasheet SDS

Mouse Anti-CLEC10A Recombinant Antibody (CBLC-LY-012) (V2LY-1206-LY71)

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Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLC-LY-012
Application*: F
Datasheet SDS

Rabbit Anti-CLEC10A Recombinant Antibody (019) (V2LY-1206-LY69)

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Target: CLEC10A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 019
Application*: E
Datasheet SDS

Mouse Anti-CLEC10A Recombinant Antibody (CBYY-C1314) (CBMAB-C2752-YY)

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Target: CLEC10A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle
Clone: CBYY-C1314
Application*: F, WB, IH, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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