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Mouse Anti-CLEC10A Recombinant Antibody (CBXC-0461) (V2LY-1206-LY77)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXC-0461
Antibody Isotype
IgG1
Application
FC, WB, IHC, IP

Basic Information

Immunogen
CD301 was used as immunogen.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:100-1:2,000
IP1:10-1:500
IHC1:10-1:500
FC1:10-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Tris-NaCl
Preservative
None
Concentration
0.5 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
C-type lectin domain family 10, member A
Entrez Gene ID
10462
UniProt ID
Q8IUN9
Function
Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
Biological Process
Adaptive immune response Source: UniProtKB-KW
Endocytosis Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Stimulatory C-type lectin receptor signaling pathway Source: Reactome
Cellular Location
Membrane
Topology
Cytoplasmic: 1-39
Helical: 40-60
Extracellular: 61-316
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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