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Mouse Anti-APOE Recombinant Antibody (D6E10) (CBMAB-0078CQ)

This product is a mouse antibody that recognizes APOE. The antibody D6E10 can be used for immunoassay techniques such as: FC, IF, IHC-Fr, IHC-P, IP, WB.
Host Species
Mouse
Application
FC, IF, IHC-Fr, IHC-P, IP, WB
Immunogen
Synthetic peptide from Apolipoprotein E aa 141-160
Antibody Isotype
IgG1
Specificity
Mouse, Human, Zebrafish
Clone
D6E10
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
Apolipoprotein E is the recognition site for receptors involved in the clearance of remnants of very low density lipoproteins and chylomicrons. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. The E2 variant binds less readily. Weisgraber et al. showed that human E apoprotein of the E2 form, which contains cysteine (rather than arginine) at both of the 2 variable sites, binds poorly with cell surface receptors, whereas E3 and E4 bind well.
Alternative Name
Apolipoprotein E; APO-E; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); Apolipoprotein E3; LDLCQ5; LPG; AD2
Entrez Gene ID
Human348
Mouse11816
Zebrafish553587
UniProt ID
HumanP02649
MouseP08226
ZebrafishO42364
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For research use only. Not intended for any clinical use.
Cat CBMAB-0078CQ
Conjugates
Size
Price $
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Second antibody and isotype control