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Rat Anti-CLEC9A Recombinant Antibody (15H30) (CBMAB-C3279-LY)

This product is antibody recognizes CLEC9A. The antibody 15H30 immunoassay techniques such as: WB.
See all CLEC9A antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
15H30
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Recombinant protein corresponding to mouse CLEC9a
Specificity
Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
0.2 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
C-Type Lectin Domain Containing 9A
Introduction
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]
Entrez Gene ID
UniProt ID
Function
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Biological Process
Positive regulation of cytokine production Source: UniProtKB
Receptor-mediated endocytosis Source: UniProtKB
Cellular Location
Membrane
Topology
Cytoplasmic: 1-35
Helical: 36-56
Extracellular: 57-241
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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