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Rat Anti-CLEC9A Recombinant Antibody (397) (CBMAB-C0174-YY)

This product is rat antibody that recognizes CLEC9A. The antibody 397 can be used for immunoassay techniques such as: WB
See all CLEC9A antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
397
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope
Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein G purified
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
C-Type Lectin Domain Containing 9A
Entrez Gene ID
232414
UniProt ID
Q8BRU4
Alternative Names
Carboxypeptidase B1; Pancreatic Carboxypeptidase B; Carboxypeptidase B1 (Tissue); Tissue Carboxypeptidase B; Pancreas-Specific Protein; Protaminase; EC 3.4.17.2;
Function
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Biological Process
Positive regulation of cytokine production Source: UniProtKB
Receptor-mediated endocytosis Source: UniProtKB
Cellular Location
Membrane
Topology
Cytoplasmic: 1-35
Helical: 36-56
Extracellular: 57-241
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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