Rat Anti-CLEC9A Recombinant Antibody (AG53) (V2LY-0524-LY104)

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Basic Information

Host Animal
Rat
Clone
AG53
Application
FC, IF, WB
Immunogen
RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope
Host Species
Rat
Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Endotoxin
< 1.0 EU/mg as determined by the LAL method
Format
Liquid
Buffer
PBS
Preservative
None
Concentration
5 mg/ml
Purity
>95% by SDS Page
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
C-Type Lectin Domain Containing 9A
Entrez Gene ID
UniProt ID
Alternative Names
C-Type Lectin Domain Containing 9A; C-Type Lectin Domain Family 9 Member A; C-Type Lectin Domain Family 9, Member A; HEEE9341; UNQ9341; DNGR-1; CD370; DNGR1;
Function
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Biological Process
Positive regulation of cytokine production Source: UniProtKB
Receptor-mediated endocytosis Source: UniProtKB
Cellular Location
Membrane
Topology
Cytoplasmic: 1-35
Helical: 36-56
Extracellular: 57-241
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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