Rat Anti-CLEC9A Recombinant Antibody (C8401) (CBMAB-C8401-LY)

Name: Rat Anti-CLEC9A Recombinant Antibody (C8401)
SKU: CBMAB-C8401-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

C8401

Application

IHC

Immunogen

CHO-derived recombinant mouse CLEC9a Lys57-Ile264.

Host Species

Rat

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
IHC	8-25 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, Trehalose

Preservative

None

Concentration

0.5 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

C-Type Lectin Domain Containing 9A

Introduction

CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]

Entrez Gene ID

232414

UniProt ID

Q8BRU4

Alternative Names

C-Type Lectin Domain Containing 9A; C-Type Lectin Domain Family 9 Member A; C-Type Lectin Domain Family 9, Member A; HEEE9341; UNQ9341; DNGR-1; CD370; DNGR1;

Function

Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.

Biological Process

Positive regulation of cytokine production Source: UniProtKB
Receptor-mediated endocytosis Source: UniProtKB

Cellular Location

Membrane

Topology

Cytoplasmic: 1-35
Helical: 36-56
Extracellular: 57-241

PTM

N-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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