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Mouse Anti-CLGN Recombinant Antibody (14i124) (CBMAB-C3048-LY)

This product is antibody recognizes CLGN. The antibody 14i124 immunoassay techniques such as: ELISA, IHC-F, WB.
See all CLGN antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
14i124
Antibody Isotype
IgG
Application
ELISA, IHC-F, WB

Basic Information

Immunogen
Recombinant protein corresponding to aa249-405 from expressed in E. coli
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.5% protein stabilizer
Preservative
0.05% sodium azide
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
calmegin
Introduction
Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. [provided by RefSeq, Jul 2008]
Entrez Gene ID
1047
UniProt ID
O14967
Alternative Names
Calmegin; Testis Tissue Sperm-Binding Protein Li 79P;
Function
Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions (By similarity).
Biological Process
Binding of sperm to zona pellucida Source: Ensembl
Endoplasmic reticulum unfolded protein response Source: GO_Central
Protein-containing complex assembly Source: Ensembl
Protein folding Source: GO_Central
Single fertilization Source: ProtInc
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 20-471
Helical: 472-492
Cytoplasmic: 493-610
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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