CLGN

Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. [provided by RefSeq]
Full Name
calmegin
Function
Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions (By similarity).
Biological Process
Binding of sperm to zona pellucida Source: Ensembl
Endoplasmic reticulum unfolded protein response Source: GO_Central
Protein-containing complex assembly Source: Ensembl
Protein folding Source: GO_Central
Single fertilization Source: ProtInc
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 20-471
Helical: 472-492
Cytoplasmic: 493-610
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Anti-CLGN antibodies

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Mouse Anti-CLGN Recombinant Antibody (CBT2637) (V2LY-0625-LY985)

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Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2637
Application*: WB, IH, IC, F
Datasheet SDS

Mouse Anti-CLGN Recombinant Antibody (CBT2158) (V2LY-0625-LY984)

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Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2158
Application*: WB, IH, IC
Datasheet SDS

Mouse Anti-CLGN Recombinant Antibody (CBT2171) (V2LY-0625-LY2846)

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Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2171
Application*: WB, IH, IC
Datasheet SDS

Mouse Anti-CLGN Recombinant Antibody (9C8G10) (V2LY-1206-LY214)

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Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9C8G10
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-CLGN Recombinant Antibody (CBXC-2496) (V2LY-1206-LY213)

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Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2496
Application*: E
Datasheet SDS

Mouse Anti-CLGN Recombinant Antibody (CBXC-1746) (V2LY-1206-LY212)

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Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1746
Application*: WB, P
Datasheet SDS

Mouse Anti-CLGN Recombinant Antibody (CBXC-0470) (V2LY-1206-LY211)

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Target: CLGN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0470
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CLGN Recombinant Antibody (1C8B6) (V2LY-1206-LY210)

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Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C8B6
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-CLGN Recombinant Antibody (3B5) (V2LY-1206-LY209)

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Target: CLGN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3B5
Application*: E, WB
Datasheet SDS

Rabbit Anti-CLGN Recombinant Antibody (1384) (V2LY-1206-LY208)

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Target: CLGN
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 1384
Application*: WB, P, IF, IP, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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