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CLGN

Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. [provided by RefSeq]
Full Name
calmegin
Function
Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions (By similarity).
Biological Process
Binding of sperm to zona pellucida Source: Ensembl
Endoplasmic reticulum unfolded protein response Source: GO_Central
Protein-containing complex assembly Source: Ensembl
Protein folding Source: GO_Central
Single fertilization Source: ProtInc
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 20-471
Helical: 472-492
Cytoplasmic: 493-610

Anti-CLGN antibodies

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Mouse Anti-CLGN Recombinant Antibody (9C8G10) (CBMAB-C3906WJ)

Datasheet SDS
Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9C8G10
Application*: WB, E, IH, IC

Mouse Anti-CLGN Recombinant Antibody (CBXC-2496) (CBMAB-C3668-CQ)

Datasheet SDS
Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2496
Application*: WB, E, IH, IF

Mouse Anti-CLGN Recombinant Antibody (CBXC-1746) (CBMAB-C3667-CQ)

Datasheet SDS
Target: CLGN
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1746
Application*: WB, IP, IF, E

Mouse Anti-CLGN Recombinant Antibody (CBXC-0470) (CBMAB-C3666-CQ)

Datasheet SDS
Target: CLGN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0470
Application*: SE, E, WB

Mouse Anti-CLGN (AA 249-405) Recombinant Antibody (1C8B6) (CBMAB-C2007-FY)

Datasheet SDS
Target: CLGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C8B6
Application*: E, IF, IH, P, WB

Rabbit Anti-CLGN Recombinant Antibody (EPR11832-11) (CBMAB-1384-CN)

Datasheet SDS
Target: CLGN
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Chimpanzee
Clone: EPR11832-11
Application*: WB, P, IF, IP, F

Mouse Anti-CLGN Recombinant Antibody (CBLC163-LY) (CBMAB-C11044-LY)

Datasheet SDS
Target: CLGN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBLC163-LY
Application*: WB

Mouse Anti-CLGN Recombinant Antibody (CBCNC-210) (CBMAB-C2468-CN)

Datasheet SDS
Target: CLGN
Host: Mouse
Specificity: Rat
Clone: CBCNC-210
Application*: WB, ICC, P, IH-F, E

Mouse Anti-CLGN Recombinant Antibody (CBCNC-209) (CBMAB-C2467-CN)

Datasheet SDS
Target: CLGN
Host: Mouse
Specificity: Human
Clone: CBCNC-209
Application*: WB, ICC, P, IH-F, E

Mouse Anti-CLGN Recombinant Antibody (14i122) (CBMAB-C2465-CN)

Datasheet SDS
Target: CLGN
Host: Mouse
Specificity: Human
Clone: 14i122
Application*: E, IH, WB

Mouse Anti-CLGN Recombinant Antibody (3B5) (CBMAB-C5729-LY)

Datasheet SDS
Target: CLGN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3B5
Application*: E, WB

Mouse Anti-CLGN Recombinant Antibody (14i124) (CBMAB-C3048-LY)

Datasheet SDS
Target: CLGN
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 14i124
Application*: E, C, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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