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Mouse Anti-GPRC5C Recombinant Antibody (CBFYH-0464) (CBMAB-H0521-FY)

This product is mouse antibody that recognizes GPRC5C. The antibody CBFYH-0464 can be used for immunoassay techniques such as: FC.
See all GPRC5C antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-0464
Antibody Isotype
IgG2a
Application
FC, CyTOF-ready

Basic Information

Immunogen
NS0 mouse myeloma cell line transfected with recombinant human GPRC5C
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, trehalose
Concentration
0.2 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
G protein-coupled receptor class C group 5 member C
Introduction
The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
UniProt ID
Alternative Names
G Protein-Coupled Receptor Class C Group 5 Member C; Retinoic Acid-Induced Gene 3 Protein; RAIG-3; RAIG3; G Protein-Coupled Receptor, Family C, Group 5, Member C; G Protein-Coupled Receptor, Class C, Group 5, Member C; G-Protein Coupled Receptor Family C Group 5 Member C; Retinoic Acid Responsive Gene Protein; Orphan G-Protein Coupled Receptor
Function
This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Biological Process
G protein-coupled receptor signaling pathway Source: ProtInc
Cellular Location
Cell membrane; Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
Topology
Extracellular: 24-50
Helical: 51-71
Cytoplasmic: 72-85
Helical: 86-106
Extracellular: 107-120
Helical: 121-141
Cytoplasmic: 142-155
Helical: 156-176
Extracellular: 177-208
Helical: 209-229
Cytoplasmic: 230-241
Helical: 242-262
Extracellular: 263-279
Helical: 280-300
Cytoplasmic: 301-441
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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