Mouse Anti-GPRC5C Recombinant Antibody (CBFYH-0464) (CBMAB-H0521-FY)

Name: Mouse Anti-GPRC5C Recombinant Antibody (CBFYH-0464)
SKU: CBMAB-H0521-FY
Rating: 5 (1 reviews)

See all GPRC5C antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-0464

Application

FC, CyTOF-ready

Immunogen

NS0 mouse myeloma cell line transfected with recombinant human GPRC5C

Specificity

Human

Antibody Isotype

IgG2a

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, trehalose

Concentration

0.2 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

G protein-coupled receptor class C group 5 member C

Introduction

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene.

Entrez Gene ID

55890

UniProt ID

Q9NQ84

Alternative Names

G Protein-Coupled Receptor Class C Group 5 Member C; Retinoic Acid-Induced Gene 3 Protein; RAIG-3; RAIG3; G Protein-Coupled Receptor, Family C, Group 5, Member C; G Protein-Coupled Receptor, Class C, Group 5, Member C; G-Protein Coupled Receptor Family C Group 5 Member C; Retinoic Acid Responsive Gene Protein; Orphan G-Protein Coupled Receptor

Function

This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.

Biological Process

G protein-coupled receptor signaling pathway Source: ProtInc

Cellular Location

Cell membrane; Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.

Topology

Extracellular: 24-50
Helical: 51-71
Cytoplasmic: 72-85
Helical: 86-106
Extracellular: 107-120
Helical: 121-141
Cytoplasmic: 142-155
Helical: 156-176
Extracellular: 177-208
Helical: 209-229
Cytoplasmic: 230-241
Helical: 242-262
Extracellular: 263-279
Helical: 280-300
Cytoplasmic: 301-441

Zhang, Y. W., Mess, J., Aizarani, N., Mishra, P., Johnson, C., Romero-Mulero, M. C., ... & Cabezas-Wallscheid, N. (2022). Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells. Nature Cell Biology, 24(7), 1038-1048.

Zhang, Y., Mess, J., Aizarani, N., Mishra, P., Johnson, C., Romero-Mulero, M. C., ... & Wallscheid, N. C. (2022). 2024–GPRC5C IS CRITICAL FOR HEALTHY HEMATOPOIESIS AND ACUTE MYELOID LEUKEMIA. Experimental Hematology, 111, S43.

May, C. L., Ward, A. K., Dahlen, C. R., Swanson, K. C., Ringwall, K. A., & Hulsman Hanna, L. L. (2019). PSI-19 Bovine chromosome 19 VDR and GPRC5C genotypes are associated with udder conformation traits in crossbred beef cattle. Journal of Animal Science, 97(Supplement_2), 241-242.

Rajkumar, P., Cha, B., Yin, J., Arend, L. J., Păunescu, T. G., Hirabayashi, Y., ... & Pluznick, J. L. (2018). Identifying the localization and exploring a functional role for Gprc5c in the kidney. The FASEB Journal, 32(4), 2046.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-GPRC5C Recombinant Antibody (CBFYH-0464)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rabbit Anti-GPRC5C Recombinant Antibody (EG1414) (CAT#: CBMAB-EN1693-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry