GPRC5C

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene.

G protein-coupled receptor class C group 5 member C

This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.

G protein-coupled receptor signaling pathway Source: ProtInc

Cell membrane; Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.

Extracellular: 24-50
Helical: 51-71
Cytoplasmic: 72-85
Helical: 86-106
Extracellular: 107-120
Helical: 121-141
Cytoplasmic: 142-155
Helical: 156-176
Extracellular: 177-208
Helical: 209-229
Cytoplasmic: 230-241
Helical: 242-262
Extracellular: 263-279
Helical: 280-300
Cytoplasmic: 301-441