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GPRC5C

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene.

Full Name

G protein-coupled receptor class C group 5 member C

Function

This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.

Biological Process

G protein-coupled receptor signaling pathway Source: ProtInc

Cellular Location

Cell membrane; Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.

Topology

Extracellular: 24-50
Helical: 51-71
Cytoplasmic: 72-85
Helical: 86-106
Extracellular: 107-120
Helical: 121-141
Cytoplasmic: 142-155
Helical: 156-176
Extracellular: 177-208
Helical: 209-229
Cytoplasmic: 230-241
Helical: 242-262
Extracellular: 263-279
Helical: 280-300
Cytoplasmic: 301-441

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Anti-GPRC5C antibodies

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Mouse Anti-GPRC5C Recombinant Antibody (CBFYH-0464) (CBMAB-H0521-FY)

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Target: GPRC5C

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYH-0464

Application*: F

Rabbit Anti-GPRC5C Recombinant Antibody (EG1414) (CBMAB-EN1693-LY)

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Target: GPRC5C

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: EG1414

Application*: WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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