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Mouse Anti-CPNE6 Recombinant Antibody (CBWJC-3026) (CBMAB-C4182WJ)

This product is a Mouse antibody that recognizes CPNE6. This antibody CBWJC-3026 can be used for immunoassay techniques such as: ELISA, WB.
See all CPNE6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-3026
Antibody Isotype
IgG
Application
ELISA, WB

Basic Information

Immunogen
Recombinant human copine 6 protein with GST tag
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
copine VI (neuronal)
Introduction
CPNE6 (Copine 6) is a Protein Coding gene. Diseases associated with CPNE6 include Presbyopia and Eye Accommodation Disease. Among its related pathways are Metabolism and Glycerophospholipid biosynthesis. Gene Ontology (GO) annotations related to this gene include calcium ion binding and phosphatidylserine binding. An important paralog of this gene is CPNE7.
Entrez Gene ID
9362
UniProt ID
O95741
Alternative Names
Copine 6; Copine VI (Neuronal); N-Copine; Neuronal-Copine; Copine VI; Copine-6;
Function
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Binds phospholipid membranes in a calcium-dependent manner (By similarity).

Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Biological Process
Cell differentiation Source: UniProtKB-KW
Cellular response to calcium ion Source: GO_Central
Chemical synaptic transmission Source: ProtInc
Glycerophospholipid biosynthetic process Source: Reactome
Lipid metabolic process Source: ProtInc
Nervous system development Source: ProtInc
Positive regulation of dendrite extension Source: UniProtKB
Vesicle-mediated transport Source: ProtInc
Cellular Location
Endosome; Cell membrane; Cytoplasm; Clathrin-coated vesicle; Perikaryon; Dendrite. Mainly cytoplasmic in absence of calcium. Associated predominantly with membranes in presence of calcium. Translocates to the cell membrane in a calcium-dependent manner. Colocalized with transferrin in intracellular clathrin-coated membrane vesicles in a calcium-dependent manner.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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