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Mouse Anti-CSPG5 Recombinant Antibody (CBYY-C2199) (CBMAB-C3637-YY)

This product is mouse antibody that recognizes CSPG5. The antibody CBYY-C2199 can be used for immunoassay techniques such as: ELISA, WB
See all CSPG5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C2199
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa445-539 from human CSPG5 (NP_006565) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein A purified
Preservative
PBS, pH 7.2
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Chondroitin Sulfate Proteoglycan 5
Entrez Gene ID
10675
UniProt ID
O95196
Alternative Names
Cancer/Testis Antigen 1B; Autoimmunogenic Cancer/Testis Antigen NY-ESO-1; Cancer/Testis Antigen 6.1; L Antigen Family Member 2; Cancer/Testis Antigen 1; LAGE-2; LAGE2B; CT6.1; CTAG1;
Function
May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.
Biological Process
Cell projection morphogenesis Source: GO_Central
Chondroitin sulfate biosynthetic process Source: Reactome
Chondroitin sulfate catabolic process Source: Reactome
Cytoskeleton organization Source: UniProtKB
Dermatan sulfate biosynthetic process Source: Reactome
Glial cell projection elongation Source: UniProtKB
Intracellular transport Source: UniProtKB
Nervous system development Source: UniProtKB
Positive regulation of substrate adhesion-dependent cell spreading Source: UniProtKB
Regulation of growth Source: UniProtKB-KW
Regulation of synaptic vesicle exocytosis Source: Ensembl
Trans-synaptic signaling, modulating synaptic transmission Source: GO_Central
Cellular Location
Endoplasmic reticulum membrane; Cell membrane; Synaptic cell membrane; Golgi apparatus membrane; Cell surface. In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts.
Topology
Extracellular: 31-423
Helical: 424-444
Cytoplasmic: 445-566
PTM
N-glycosylated.
O-glycosylated; contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissues maturation (By similarity).
Phosphorylated; in intracellular and extracellular parts.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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