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Mouse Anti-CTDSP2 Recombinant Antibody (CBYY-C2261) (CBMAB-C3699-YY)

This product is mouse antibody that recognizes CTDSP2. The antibody CBYY-C2261 can be used for immunoassay techniques such as: DB, WB
See all CTDSP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C2261
Antibody Isotype
IgG2b
Application
DB, WB

Basic Information

Immunogen
Recombinant protein corresponding to a 50-200aa sequence from human CTDSP2 (NM_005730)
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein G purified
Buffer
0.1 mg/mL
Preservative
PBS, pH 7.4, 1% BSA
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
Entrez Gene ID
UniProt ID
Alternative Names
Catenin Beta 1; Catenin (Cadherin-Associated Protein), Beta 1, 88kDa; CTNNB; Catenin (Cadherin-Associated Protein), Beta 1 (88kD); Catenin (Cadherin-Associated Protein), Beta 1; Catenin Beta-1;
Function
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Biological Process
IRE1-mediated unfolded protein response Source: Reactome
Negative regulation of G1/S transition of mitotic cell cycle Source: Ensembl
Negative regulation of protein phosphorylation Source: Ensembl
Protein dephosphorylation Source: UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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