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CTDSP2

CTDSP2 (CTD Small Phosphatase 2) is a Protein Coding gene. Among its related pathways are Unfolded Protein Response (UPR) and Coregulation of Androgen receptor activity. Gene Ontology (GO) annotations related to this gene include phosphatase activity and CTD phosphatase activity. An important paralog of this gene is CTDSPL.
Full Name
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
Function
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Biological Process
IRE1-mediated unfolded protein response Source: Reactome
Negative regulation of G1/S transition of mitotic cell cycle Source: Ensembl
Negative regulation of protein phosphorylation Source: Ensembl
Protein dephosphorylation Source: UniProtKB
Cellular Location
Nucleus

Anti-CTDSP2 antibodies

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Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3320
Application*: WB, IH
Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1570
Application*: E
Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-3057
Application*: WB, IH
Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0604
Application*: E, WB
Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-2377
Application*: DB
Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBCNC-446
Application*: WB
Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBCNC-094
Application*: E, WB
Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C2261
Application*: DB, WB
Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 8C88
Application*: DB, WB
Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4F4
Application*: E, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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