CTDSP2

CTDSP2 (CTD Small Phosphatase 2) is a Protein Coding gene. Among its related pathways are Unfolded Protein Response (UPR) and Coregulation of Androgen receptor activity. Gene Ontology (GO) annotations related to this gene include phosphatase activity and CTD phosphatase activity. An important paralog of this gene is CTDSPL.
Full Name
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
Function
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Biological Process
IRE1-mediated unfolded protein response Source: Reactome
Negative regulation of G1/S transition of mitotic cell cycle Source: Ensembl
Negative regulation of protein phosphorylation Source: Ensembl
Protein dephosphorylation Source: UniProtKB
Cellular Location
Nucleus
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Anti-CTDSP2 antibodies

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Mouse Anti-CTDSP2 Recombinant Antibody (CBXC-3057) (V2LY-0125-LY244)

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Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXC-3057
Application*: WB, IH
Datasheet SDS

Mouse Anti-CTDSP2 Recombinant Antibody (CBXC-0604) (V2LY-0125-LY243)

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Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0604
Application*: WB, IH
Datasheet SDS

Mouse Anti-CTDSP2 Recombinant Antibody (CBYY-C2261) (V2LY-0125-LY242)

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Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYY-C2261
Application*: E
Datasheet SDS

Mouse Anti-CTDSP2 Recombinant Antibody (CBFYC-2377) (V2LY-0125-LY241)

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Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-2377
Application*: WB, IP
Datasheet SDS

Mouse Anti-CTDSP2 Recombinant Antibody (4F4) (V2LY-0125-LY240)

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Target: CTDSP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4F4
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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