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Mouse Anti-CTNNA3 Recombinant Antibody (892_24D2S) (CBMAB-A4359-YC)

Provided herein is a Mouse monoclonal antibody against Human Catenin Alpha 3. The antibody can be used for immunoassay techniques, such as WB, IF, ICC, IP.
See all CTNNA3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
892_24D2S
Antibody Isotype
IgG2a
Application
WB, IF, ICC, IP

Basic Information

Immunogen
Human Flt3 with Nterminal His tag, expressed in a Baculovirus infected Sf9 cell expression system
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Catenin Alpha 3
Introduction
CTNNA3 (Catenin Alpha 3) is a protein coding gene. Diseases associated with CTNNA3 include Arrhythmogenic Right Ventricular Dysplasia, Familial, 13 and Arrhythmogenic Right Ventricular Cardiomyopathy. Among its related pathways are PAK Pathway and Gastric
Entrez Gene ID
29119
UniProt ID
Q9UI47
Alternative Names
Catenin Alpha 3; Catenin (Cadherin-Associated Protein), Alpha 3; Alpha-T-Catenin; Cadherin-Associated Protein; Alpha-Catenin-Like Protein; Catenin Alpha-3; Alpha T-Catenin; ARVD13; VR22;
Function
May be involved in formation of stretch-resistant cell-cell adhesion complexes.
Biological Process
Actin filament organization Source: InterPro
Bundle of His cell-Purkinje myocyte adhesion involved in cell communication Source: BHF-UCL
Cell-cell adhesion Source: UniProtKB
Cell migration Source: GO_Central
Epithelial cell-cell adhesion Source: InterPro
Regulation of heart rate by cardiac conduction Source: BHF-UCL
Regulation of ventricular cardiac muscle cell action potential Source: BHF-UCL
Cellular Location
Cytoskeleton. Localizes to intercalated disks of cardiomyocytes and in peritubular myoid cells of testis, and colocalizes with CTNNA1 and CTNNA2.
Involvement in disease
Arrhythmogenic right ventricular dysplasia, familial, 13 (ARVD13):
A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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