CTNNA3
CTNNA3 (Catenin Alpha 3) is a Protein Coding gene. Diseases associated with CTNNA3 include Arrhythmogenic Right Ventricular Dysplasia, Familial, 13 and Arrhythmogenic Right Ventricular Cardiomyopathy. Among its related pathways are PAK Pathway and Gastric cancer. Gene Ontology (GO) annotations related to this gene include structural molecule activity and beta-catenin binding. An important paralog of this gene is CTNNA2.
Full Name
Catenin Alpha 3
Function
May be involved in formation of stretch-resistant cell-cell adhesion complexes.
Biological Process
Actin filament organization Source: InterPro
Bundle of His cell-Purkinje myocyte adhesion involved in cell communication Source: BHF-UCL
Cell-cell adhesion Source: UniProtKB
Cell migration Source: GO_Central
Epithelial cell-cell adhesion Source: InterPro
Regulation of heart rate by cardiac conduction Source: BHF-UCL
Regulation of ventricular cardiac muscle cell action potential Source: BHF-UCL
Bundle of His cell-Purkinje myocyte adhesion involved in cell communication Source: BHF-UCL
Cell-cell adhesion Source: UniProtKB
Cell migration Source: GO_Central
Epithelial cell-cell adhesion Source: InterPro
Regulation of heart rate by cardiac conduction Source: BHF-UCL
Regulation of ventricular cardiac muscle cell action potential Source: BHF-UCL
Cellular Location
Cytoskeleton. Localizes to intercalated disks of cardiomyocytes and in peritubular myoid cells of testis, and colocalizes with CTNNA1 and CTNNA2.
Involvement in disease
Arrhythmogenic right ventricular dysplasia, familial, 13 (ARVD13):
A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias.
A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias.
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Anti-CTNNA3 antibodies
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Target: CTNNA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBWJC-3354
Application*: E, WB, P
Target: CTNNA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-3074
Application*: WB, IP, E
Target: CTNNA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: A4359
Application*: WB, P
Target: CTNNA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBCNC-461
Application*: E, WB
Target: CTNNA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBWJC-3353
Application*: WB, P
Target: CTNNA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-0609
Application*: WB, IP, IF, E
Target: CTNNA3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-C2273
Application*: IF, WB
Target: CTNNA3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-C0078
Application*: IF, WB
Target: CTNNA3
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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