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Mouse Anti-CTNNBL1 Antibody (5BA14) (CBMAB-1103CQ)

This product is a mouse antibody that recognizes CTNNBL1. The antibody 5BA14 can be used for immunoassay techniques such as: ELISA.
See all CTNNBL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5BA14
Antibody Isotype
IgG1
Application
ELISA

Basic Information

Immunogen
Recombinant full length protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
CTNNBL1
Introduction
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. Diseases associated with CTNNBL1 include Sleep Disorder and Auditory Agnosia. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression.
Entrez Gene ID
56259
UniProt ID
Q8WYA6
Alternative Names
Catenin; Beta Like 1; Testis Development Protein NYD-SP19; Nuclear Associated Protein; C20orf33; NAP; Chromosome 20 Open Reading Frame 33; Nuclear-Associated Protein; DJ633O20.1; PP8304; P14L
Function
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.
Biological Process
Apoptotic process Source: UniProtKB-KW
mRNA splicing, via spliceosome Source: Reactome
Positive regulation of apoptotic process Source: UniProtKB
Somatic diversification of immunoglobulins Source: UniProtKB
Cellular Location
Isoform 1: Nucleus
Isoform 2: Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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