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Mouse Anti-CTNNBL1 Recombinant Antibody (7H6-B4-A8) (CBMAB-Z0382-LY)

The product is antibody recognizes CTNNBL1. The antibody 7H6-B4-A8 immunoassay techniques such as: WB, FC.
See all CTNNBL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
7H6-B4-A8
Antibody Isotype
IgG2a
Application
WB, FC

Basic Information

Immunogen
Purified recombinant fragment of human CTNNBL1 (AA: 390-557) expressed in E. Coli.
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
CTNNBL1
Introduction
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome.
Entrez Gene ID
56259
UniProt ID
Q8WYA6
Alternative Names
NAP; P14L; PP8304; C20orf33; dJ633O20.1
Function
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.
Biological Process
Apoptotic process Source: UniProtKB-KW
mRNA splicing, via spliceosome Source: Reactome
Positive regulation of apoptotic process Source: UniProtKB
Somatic diversification of immunoglobulins Source: UniProtKB
Cellular Location
Isoform 1: Nucleus
Isoform 2: Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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