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Rabbit Anti-DAP Recombinant Antibody (EG922) (CBMAB-EN1093-LY)

The product is antibody recognizes DAP. The antibody EG922 immunoassay techniques such as: IHC: 1:50~1:100 ELISA: 1:40000.
See all DAP antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse
Clone
EG922
Antibody Isotype
IgG
Application
IHC: 1:50~1:100 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human DAP.
Specificity
Human, Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Death Associated Protein
Introduction
This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Entrez Gene ID
Human1611
Mouse223453
UniProt ID
HumanP51397
Alternative Names
Death Associated Protein; DAP-1; Death-Associated Protein 1; DAP1;
Function
Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death.
Biological Process
Activation of cysteine-type endopeptidase activity involved in apoptotic process Source: UniProtKB
Apoptotic process Source: MGI
Apoptotic signaling pathway Source: UniProtKB
Autophagy Source: UniProtKB-KW
Cellular response to amino acid starvation Source: UniProtKB
Negative regulation of autophagy Source: UniProtKB
Negative regulation of NF-kappaB transcription factor activity Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
PTM
Phosphorylated. Phosphorylation by MTOR inhibits the suppressive activity of DAP toward autophagy.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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