Sign in or Register   Sign in or Register
  |  

Rabbit Anti-DUSP9 Recombinant Antibody (EG1008) (CBMAB-EN1191-LY)

The product is antibody recognizes DUSP9. The antibody EG1008 immunoassay techniques such as: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000.
See all DUSP9 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1008
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human DUSP9.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Dual Specificity Phosphatase 9
Introduction
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Entrez Gene ID
Human1852
Mouse75590
Rat293847
UniProt ID
HumanQ99956
MouseQ7TNL7
RatQ2YDV1
Alternative Names
Dual Specificity Phosphatase 9; Map Kinase Phosphatase 4; Mitogen-Activated Protein Kinase Phosphatase 4; MKP-4; MKP4; Serine/Threonine Specific Protein Phosphatase; Dual Specificity Protein Phosphatase 9; EC 3.1.3.16; EC 3.1.3.48;
Research Area
Inactivates MAP kinases. Has a specificity for the ERK family.
Biological Process
Activation of MAPK activity Source: Reactome
Inactivation of MAPK activity Source: GO_Central
JNK cascade Source: ProtInc
MAPK cascade Source: Reactome
Negative regulation of ERK1 and ERK2 cascade Source: GO_Central
Peptidyl-threonine dephosphorylation Source: GO_Central
Peptidyl-tyrosine dephosphorylation Source: GO_Central
Positive regulation of apoptotic process Source: GO_Central
Protein dephosphorylation Source: GO_Central
Regulation of heart growth Source: GO_Central
Cellular Location
Cytoplasm
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-DUSP9 Recombinant Antibody (EG1008)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare