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Mouse Anti-CELA1 Recombinant Antibody (4H5) (CBMAB-A2556-LY)

The product is antibody recognizes ELA1. The antibody 4H5 immunoassay techniques such as: WB, ELISA.
See all CELA1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4H5
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
ELA1 (NP_001962.3, 159 a.a. ~ 257 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Chymotrypsin Like Elastase Family Member 1
Introduction
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq]
Entrez Gene ID
1990
UniProt ID
Q9UNI1
Function
Acts upon elastin.
Biological Process
Elastin catabolic process Source: Ensembl
Exocrine pancreas development Source: Ensembl
Inflammatory response Source: Ensembl
Multicellular organism growth Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Pancreas morphogenesis Source: Ensembl
Positive regulation of angiogenesis Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Post-embryonic development Source: Ensembl
Proteolysis Source: GO_Central
Regulation of cell differentiation Source: Ensembl
Regulation of cell population proliferation Source: Ensembl
Tissue remodeling Source: Ensembl
Wnt signaling pathway Source: Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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