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Mouse Anti-ENO3 Recombinant Antibody (5D1) (CBMAB-A2617-LY)

The product is antibody recognizes ENO3. The antibody 5D1 immunoassay techniques such as: WB, ELISA.
See all ENO3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5D1
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
ENO3 (AAH17249, 1 a.a. ~ 434 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
enolase 3 (beta, muscle)
Introduction
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in skeletal muscle cells in the adult. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene can be associated with metabolic myopathies that may result from decreased stability of the enzyme. Two transcripts have been identified for this gene that differ only in their 5' UTR. [provided by RefSeq]
Entrez Gene ID
UniProt ID
Alternative Names
MSE
Research Area
Appears to have a function in striated muscle development and regeneration.
Biological Process
Aging Source: Ensembl
Glycolytic process Source: GO_Central
Regulation of vacuole fusion, non-autophagic Source: GO_Central
Response to drug Source: Ensembl
Skeletal muscle tissue regeneration Source: Ensembl
Cellular Location
Cytoplasm. Localized to the Z line. Some colocalization with CKM at M-band (By similarity).
Involvement in disease
Glycogen storage disease 13 (GSD13):
A metabolic disorder that results in exercise-induced myalgias, generalized muscle weakness and fatigability. It is characterized by increased serum creatine kinase and decreased enolase 3 activity. Dramatically reduced protein levels with focal sarcoplasmic accumulation of glycogen-beta particles are detected on ultrastructural analysis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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