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Mouse Anti-ENO3 Recombinant Antibody (6H2) (CBMAB-BC0084-LY)

This product is antibody recognizes eNOS. The antibody 6H2 immunoassay techniques such as: WB, ELISA.
See all ENO3 antibodies
Published Data

Summary

Host Animal
Mouse
Specificity
Human
Clone
6H2
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Immunogen
Purified recombinant fragment of human eNOS expressed in E. coli.
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.03% sodium azide
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
enolase 3 (beta, muscle)
Entrez Gene ID
UniProt ID
Research Area
Appears to have a function in striated muscle development and regeneration.
Biological Process
Aging Source: Ensembl
Glycolytic process Source: GO_Central
Regulation of vacuole fusion, non-autophagic Source: GO_Central
Response to drug Source: Ensembl
Skeletal muscle tissue regeneration Source: Ensembl
Cellular Location
Cytoplasm. Localized to the Z line. Some colocalization with CKM at M-band (By similarity).
Involvement in disease
Glycogen storage disease 13 (GSD13):
A metabolic disorder that results in exercise-induced myalgias, generalized muscle weakness and fatigability. It is characterized by increased serum creatine kinase and decreased enolase 3 activity. Dramatically reduced protein levels with focal sarcoplasmic accumulation of glycogen-beta particles are detected on ultrastructural analysis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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