Sign in or Register   Sign in or Register
  |  

Rabbit Anti-ENTPD5 Recombinant Antibody (EPR3784) (CBMAB-E1380-FY)

This product is rabbit antibody that recognizes ENTPD5. The antibody EPR3784 can be used for immunoassay techniques such as: WB, IP, IHC-P, IF.
See all ENTPD5 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
EPR3784
Antibody Isotype
IgG
Application
WB, IP, IHC-P, IF

Basic Information

Immunogen
A synthetic peptide corresponding to residues in human ENTPD5 was used as an immunogen
Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
49% PBS, 50% glycerol, 0.05% BSA
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ectonucleoside triphosphate diphosphohydrolase 5
Introduction
The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.
Entrez Gene ID
Human957
Mouse12499
Rat314312
UniProt ID
HumanO75356
MouseQ9WUZ9
RatQ6P6S9
Alternative Names
PCPH; CD39L4; NTPDase-5
Research Area
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP> IDP> UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
Biological Process
de novo' posttranslational protein folding Source: UniProtKB
ATP metabolic process Source: UniProtKB
Nucleoside diphosphate catabolic process Source: GO_Central
Positive regulation of glycolytic process Source: UniProtKB
Protein N-linked glycosylation Source: UniProtKB
Regulation of phosphatidylinositol 3-kinase signaling Source: UniProtKB
Cellular Location
Endoplasmic reticulum; Secreted
PTM
N-glycosylated; high-mannose type (By similarity). Glycosylation is not essential for enzymatic activity.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-ENTPD5 Recombinant Antibody (EPR3784)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare