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Mouse Anti-EXOC3 Recombinant Antibody (9H5) (CBMAB-1537-CN)

This product is a mouse antibody that recognizes EXOC3 of rat. The antibody 9H5 can be used for immunoassay techniques such as: WB.
See all EXOC3 antibodies
Published Data
Fig.1 Confocal images showing Sec6 localization in NMuMG cells expressing shLuc, shPar3 or shPar3 with myr-mApple-PAR3(710-1089).
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Fig.2 Immunoblot analysis of proteins identified in fraction 5 (IMCD DRM fraction).
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Summary

Host Animal
Mouse
Specificity
Rat, Mouse, Sheep, Rabbit, Chicken, Hamster, Cattle, Dog, Human, Pig, Monkey
Clone
9H5
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
Recombinant full length rSec6 protein (Rat)
Specificity
Rat, Mouse, Sheep, Rabbit, Chicken, Hamster, Cattle, Dog, Human, Pig, Monkey
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 50% Glycerol, pH 7.2
Preservative
0.09% Sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
exocyst complex component 3
Introduction
This gene is a component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Entrez Gene ID
Human11336
Mouse211446
Rat252881
Pig100624948
Cattle513138
Dog478633
Chicken420987
Hamster101828863
Monkey708422
Rabbit100356252
Sheep101103266
UniProt ID
HumanO60645
MouseQ6KAR6
RatQ62825
PigA0A480TWJ1
CattleQ0V8C2
DogF1PX56
ChickenF1NHD9
HamsterA0A1U7QDT1
MonkeyA0A2K5UMY4
RabbitG1T0H9
SheepW5Q2L6
Alternative Names
Sec6; rSec6; Sec6l1
Research Area
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Biological Process
Exocyst localization Source: GO_Central
Exocytosis Source: GO_Central
Protein transport Source: UniProtKB-KW
Cellular Location
Cytoplasm; Golgi apparatus; Perinuclear region; Growth cone; Midbody; Neuron projection. Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (PubMed:18756269).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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