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Mouse Anti-EXOC3 Recombinant Antibody (CBCNR-822) (CBMAB-R0529-CN)

This product is a Mouse antibody that recognizes EXOC3. The antibody CBCNR-822 can be used for immunoassay techniques such as: WB, IF.
See all EXOC3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-822
Antibody Isotype
IgG2b
Application
WB, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL

Target

Full Name
exocyst complex component 3
Introduction
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
Entrez Gene ID
11336
UniProt ID
O60645
Alternative Names
Exocyst Complex Component 3; Exocyst Complex Component Sec6; SEC6L1; SEC6; SEC6-Like 1 (S. Cerevisiae); Sec 6 Homolog; SEC6-Like 1; Sec6p;
Research Area
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Biological Process
Exocyst localization Source: GO_Central
Exocytosis Source: GO_Central
Protein transport Source: UniProtKB-KW
Cellular Location
Cytoplasm; Golgi apparatus; Perinuclear region; Growth cone; Midbody; Neuron projection. Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (PubMed:18756269).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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